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2i14

From Proteopedia

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(New page: 200px<br /><applet load="2i14" size="350" color="white" frame="true" align="right" spinBox="true" caption="2i14, resolution 2.90&Aring;" /> '''Crystal structure of...)
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[[Image:2i14.gif|left|200px]]<br /><applet load="2i14" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2i14, resolution 2.90&Aring;" />
 
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'''Crystal structure of nicotinate-nucleotide pyrophosphorylase from Pyrococcus furiosus'''<br />
 
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==About this Structure==
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==Crystal structure of nicotinate-nucleotide pyrophosphorylase from Pyrococcus furiosus==
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2I14 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=PCP:'>PCP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I14 OCA].
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<StructureSection load='2i14' size='340' side='right'caption='[[2i14]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2i14]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I14 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I14 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PCP:1-ALPHA-PYROPHOSPHORYL-2-ALPHA,3-ALPHA-DIHYDROXY-4-BETA-CYCLOPENTANE-METHANOL-5-PHOSPHATE'>PCP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i14 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i14 OCA], [https://pdbe.org/2i14 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i14 RCSB], [https://www.ebi.ac.uk/pdbsum/2i14 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i14 ProSAT], [https://www.topsan.org/Proteins/BSGC/2i14 TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8TZS9_PYRFU Q8TZS9_PYRFU]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i1/2i14_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i14 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
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[[Category: Single protein]]
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[[Category: Kim R]]
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[[Category: BSGC, Berkeley.Structural.Genomics.Center.]]
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[[Category: Kim S-H]]
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[[Category: Kim, R.]]
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[[Category: Shin DH]]
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[[Category: Kim, S.H.]]
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[[Category: Shin, D.H.]]
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[[Category: PCP]]
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[[Category: ZN]]
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[[Category: berkeley structural genomics center]]
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[[Category: bsgc]]
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[[Category: crystal structure]]
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[[Category: ligand binding]]
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[[Category: nicotinate-nucleotide pyrophosphorylase]]
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[[Category: phosphoribosylpyrophosphate]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomics]]
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[[Category: zn metal ion]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 20:32:39 2008''
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Current revision

Crystal structure of nicotinate-nucleotide pyrophosphorylase from Pyrococcus furiosus

PDB ID 2i14

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