3sua

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(New page: '''Unreleased structure''' The entry 3sua is ON HOLD Authors: Bell, C.H., Aricescu, A.R., Jones, E.Y., Siebold, C. Description: Crystal structure of the intracellular domain of Plexin-...)
Current revision (09:57, 1 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 3sua is ON HOLD
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==Crystal structure of the intracellular domain of Plexin-B1 in complex with Rac1==
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<StructureSection load='3sua' size='340' side='right'caption='[[3sua]], [[Resolution|resolution]] 4.39&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3sua]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SUA FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.39&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sua OCA], [https://pdbe.org/3sua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sua RCSB], [https://www.ebi.ac.uk/pdbsum/3sua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sua ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PLXB1_HUMAN PLXB1_HUMAN] Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.<ref>PMID:12198496</ref> <ref>PMID:12196628</ref> <ref>PMID:15210733</ref> <ref>PMID:19843518</ref> <ref>PMID:20877282</ref> <ref>PMID:21912513</ref>
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Authors: Bell, C.H., Aricescu, A.R., Jones, E.Y., Siebold, C.
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==See Also==
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*[[Plexin 3D structures|Plexin 3D structures]]
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Description: Crystal structure of the intracellular domain of Plexin-B1 in complex with Rac1
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*[[Rac 3D structures|Rac 3D structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Aricescu AR]]
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[[Category: Bell CH]]
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[[Category: Jones EY]]
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[[Category: Siebold C]]

Current revision

Crystal structure of the intracellular domain of Plexin-B1 in complex with Rac1

PDB ID 3sua

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