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3sud
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3sud is ON HOLD Authors: Schiffer, C.A., Romano, K.P. Description: Crystal structure of NS3/4A protease in complex with MK-5172) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of NS3/4A protease in complex with MK-5172== | |
| + | <StructureSection load='3sud' size='340' side='right'caption='[[3sud]], [[Resolution|resolution]] 1.96Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3sud]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_C_virus_genotype_1a Hepatitis C virus genotype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SUD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SUD FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SUE:(1AR,5S,8S,10R,22AR)-5-TERT-BUTYL-N-{(1R,2S)-1-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-2-ETHENYLCYCLOPROPYL}-14-METHOXY-3,6-DIOXO-1,1A,3,4,5,6,9,10,18,19,20,21,22,22A-TETRADECAHYDRO-8H-7,10-METHANOCYCLOPROPA[18,19][1,10,3,6]DIOXADIAZACYCLONONADECINO[11,12-B]QUINOXALINE-8-CARBOXAMIDE'>SUE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sud OCA], [https://pdbe.org/3sud PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sud RCSB], [https://www.ebi.ac.uk/pdbsum/3sud PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sud ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A8DG50_9HEPC A8DG50_9HEPC] | ||
| - | + | ==See Also== | |
| - | + | *[[Virus protease 3D structures|Virus protease 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Hepatitis C virus genotype 1a]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Romano KP]] | ||
| + | [[Category: Schiffer CA]] | ||
Current revision
Crystal structure of NS3/4A protease in complex with MK-5172
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