3sv9
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3sv9 is ON HOLD Authors: Schiffer, C.A., Romano, K.P. Description: Crystal structure of NS3/4A protease variant A156T in complex with Telaprevir) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of NS3/4A protease variant A156T in complex with Telaprevir== | |
| + | <StructureSection load='3sv9' size='340' side='right'caption='[[3sv9]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3sv9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_C_virus_genotype_1a Hepatitis C virus genotype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SV9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SV9 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SV6:(1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(2R,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide'>SV6</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sv9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sv9 OCA], [https://pdbe.org/3sv9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sv9 RCSB], [https://www.ebi.ac.uk/pdbsum/3sv9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sv9 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A8DG50_9HEPC A8DG50_9HEPC] | ||
| - | + | ==See Also== | |
| - | + | *[[Virus protease 3D structures|Virus protease 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Hepatitis C virus genotype 1a]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Romano KP]] | ||
| + | [[Category: Schiffer CA]] | ||
Current revision
Crystal structure of NS3/4A protease variant A156T in complex with Telaprevir
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