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3swd
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3swd is ON HOLD Authors: Zhu, J.-Y., Schonbrunn, E. Description: E. coli MurA in complex with UDP-N-acetylmuramic acid and covalent adduct of PEP w...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==E. coli MurA in complex with UDP-N-acetylmuramic acid and covalent adduct of PEP with Cys115== | |
| + | <StructureSection load='3swd' size='340' side='right'caption='[[3swd]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3swd]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SWD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SWD FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPZ:(2R)-2-{[(2R,3R,4R,5S,6R)-3-(ACETYLAMINO)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-5-HYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-4-YL]OXY}PROPANOIC+ACID'>EPZ</scene>, <scene name='pdbligand=IAS:BETA-L-ASPARTIC+ACID'>IAS</scene>, <scene name='pdbligand=QPA:S-[(1S)-1-CARBOXY-1-(PHOSPHONOOXY)ETHYL]-L-CYSTEINE'>QPA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3swd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3swd OCA], [https://pdbe.org/3swd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3swd RCSB], [https://www.ebi.ac.uk/pdbsum/3swd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3swd ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MURA_ECOLI MURA_ECOLI] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. Target for the antibiotic phosphomycin.[HAMAP-Rule:MF_00111] | ||
| - | + | ==See Also== | |
| - | + | *[[Enoylpyruvate transferase 3D structures|Enoylpyruvate transferase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Schonbrunn E]] | ||
| + | [[Category: Zhu J-Y]] | ||
Current revision
E. coli MurA in complex with UDP-N-acetylmuramic acid and covalent adduct of PEP with Cys115
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