3p7l

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[[Image:3p7l.jpg|left|200px]]
 
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==Rat Insulin Degrading Enzyme (Insulysin)==
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The line below this paragraph, containing "STRUCTURE_3p7l", creates the "Structure Box" on the page.
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<StructureSection load='3p7l' size='340' side='right'caption='[[3p7l]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3p7l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P7L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P7L FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.0776&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_3p7l| PDB=3p7l | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p7l OCA], [https://pdbe.org/3p7l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p7l RCSB], [https://www.ebi.ac.uk/pdbsum/3p7l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p7l ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IDE_RAT IDE_RAT] Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP.
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===Rat Insulin Degrading Enzyme (Insulysin)===
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==See Also==
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*[[Insulin-degrading enzyme 3D structures|Insulin-degrading enzyme 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_21731629}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 21731629 is the PubMed ID number.
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[[Category: Rattus norvegicus]]
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[[Category: Noinaj N]]
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{{ABSTRACT_PUBMED_21731629}}
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[[Category: Rodgers DW]]
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==About this Structure==
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[[3p7l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermomicrobium_roseum Thermomicrobium roseum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P7L OCA].
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==Reference==
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<ref group="xtra">PMID:021731629</ref><references group="xtra"/>
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[[Category: Insulysin]]
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[[Category: Thermomicrobium roseum]]
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[[Category: Noinaj, N.]]
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[[Category: Rodgers, D W.]]
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[[Category: Hydrolase]]
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[[Category: Peptidase]]
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Current revision

Rat Insulin Degrading Enzyme (Insulysin)

PDB ID 3p7l

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