1c4d

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[[Image:1c4d.png|left|200px]]
 
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==GRAMICIDIN CSCL COMPLEX==
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The line below this paragraph, containing "STRUCTURE_1c4d", creates the "Structure Box" on the page.
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<StructureSection load='1c4d' size='340' side='right'caption='[[1c4d]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1c4d]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Brevibacillus_brevis Brevibacillus brevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C4D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C4D FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=ETA:ETHANOLAMINE'>ETA</scene>, <scene name='pdbligand=FVA:N-FORMYL-L-VALINE'>FVA</scene>, <scene name='pdbligand=MOH:METHANOL'>MOH</scene>, <scene name='pdbligand=PRD_000150:GRAMICIDIN+A'>PRD_000150</scene></td></tr>
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{{STRUCTURE_1c4d| PDB=1c4d | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c4d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c4d OCA], [https://pdbe.org/1c4d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c4d RCSB], [https://www.ebi.ac.uk/pdbsum/1c4d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c4d ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Gramicidin, a linear polypeptide composed of hydrophobic amino acids with alternating L- and D- configurations, forms transmembrane ion channels. The crystal structure of a gramicidin-cesium complex has been determined at 2.0 angstrom resolution. In this structure, gramicidin forms a 26 angstrom long tube comprised of two polypeptide chains arranged as antiparallel beta strands that are wrapped into a left-handed helical coil with 6.4 residues per turn. The polypeptide backbone forms the interior of the hydrophilic, solvent-filled pore and the side chains form a hydrophobic and relatively regular surface on the outside of the pore. This example of a crystal structure of a solvent-filled ion pore provides a basis for understanding the physical nature of ion translocation.
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===GRAMICIDIN CSCL COMPLEX===
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The gramicidin pore: crystal structure of a cesium complex.,Wallace BA, Ravikumar K Science. 1988 Jul 8;241(4862):182-7. PMID:2455344<ref>PMID:2455344</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 1c4d" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 2455344 is the PubMed ID number.
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{{ABSTRACT_PUBMED_2455344}}
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==About this Structure==
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[[1c4d]] is a 4 chain structure of [[Gramicidin]] with sequence from [http://en.wikipedia.org/wiki/Brevibacillus_brevis Brevibacillus brevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C4D OCA].
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==See Also==
==See Also==
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*[[Gramicidin]]
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*[[Gramicidin|Gramicidin]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:002455344</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Brevibacillus brevis]]
[[Category: Brevibacillus brevis]]
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[[Category: Wallace, B A.]]
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[[Category: Large Structures]]
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[[Category: Antibacterial]]
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[[Category: Wallace BA]]
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[[Category: Antibiotic]]
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[[Category: Antifungal]]
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[[Category: Double helix]]
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[[Category: Gramicidin]]
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[[Category: Linear gramicidin]]
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[[Category: Membrane ion channel]]
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Current revision

GRAMICIDIN CSCL COMPLEX

PDB ID 1c4d

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