3q7g

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:46, 21 February 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3q7g.png|left|200px]]
 
-
<!--
+
==Crystal Structure of E2 domain of Human Amyloid Precursor-Like Protein 1 in complex with SOS (sucrose octasulfate)==
-
The line below this paragraph, containing "STRUCTURE_3q7g", creates the "Structure Box" on the page.
+
<StructureSection load='3q7g' size='340' side='right'caption='[[3q7g]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3q7g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q7G FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GU4:2,3,4,6-TETRA-O-SULFONATO-ALPHA-D-GLUCOPYRANOSE'>GU4</scene>, <scene name='pdbligand=PRD_900013:sucrose+octasulfate'>PRD_900013</scene>, <scene name='pdbligand=YYJ:1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose'>YYJ</scene></td></tr>
-
{{STRUCTURE_3q7g| PDB=3q7g | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7g OCA], [https://pdbe.org/3q7g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q7g RCSB], [https://www.ebi.ac.uk/pdbsum/3q7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7g ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal Structure of E2 domain of Human Amyloid Precursor-Like Protein 1 in complex with SOS (sucrose octasulfate)===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/APLP1_HUMAN APLP1_HUMAN] May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I. The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis.
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_21715329}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 21715329 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_21715329}}
+
-
 
+
-
==About this Structure==
+
-
[[3q7g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7G OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:021715329</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Ha, Y.]]
+
[[Category: Large Structures]]
-
[[Category: Xue, Y.]]
+
[[Category: Ha Y]]
-
[[Category: Alzheimer's disease]]
+
[[Category: Xue Y]]
-
[[Category: Amyloid beta precursor protein]]
+
-
[[Category: E2 domain]]
+
-
[[Category: Heparin]]
+
-
[[Category: Signaling]]
+
-
[[Category: Signaling protein]]
+

Current revision

Crystal Structure of E2 domain of Human Amyloid Precursor-Like Protein 1 in complex with SOS (sucrose octasulfate)

PDB ID 3q7g

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3q7g"
Personal tools