3gkr

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3gkr" [edit=sysop:move=sysop])
Current revision (15:41, 1 November 2023) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3gkr.png|left|200px]]
 
-
<!--
+
==Crystal Structure of Weissella viridescens FemX:UDP-MurNAc-hexapeptide complex==
-
The line below this paragraph, containing "STRUCTURE_3gkr", creates the "Structure Box" on the page.
+
<StructureSection load='3gkr' size='340' side='right'caption='[[3gkr]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3gkr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus] and [https://en.wikipedia.org/wiki/Weissella_viridescens Weissella viridescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GKR FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=FGA:GAMMA-D-GLUTAMIC+ACID'>FGA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UMA:URIDINE-5-DIPHOSPHATE-N-ACETYLMURAMOYL-L-ALANINE'>UMA</scene></td></tr>
-
{{STRUCTURE_3gkr| PDB=3gkr | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gkr OCA], [https://pdbe.org/3gkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gkr RCSB], [https://www.ebi.ac.uk/pdbsum/3gkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gkr ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal Structure of Weissella viridescens FemX:UDP-MurNAc-hexapeptide complex===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/FEMX_WEIVI FEMX_WEIVI] Involved in the synthesis of the bacterial cell wall. Catalyzes the addition of alanine into the interchain peptide bridge of peptidoglycan precursor using aminoacyl-tRNA(Ala) as amino acid donor. This alanine is added to the epsilon-amino group of the L-lysine of the peptidoglycan UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine, in a ribosome-independent mechanism (PubMed:11083873, PubMed:4248527, PubMed:12679335, PubMed:15901708, PubMed:23744707). Specific for UDP-N-acetyl-muramoyl-pentapeptide. Has no activity toward UDP-N-acetyl-muramoyl-tetrapeptide or UDP-N-acetyl-muramoyl-tripeptide (PubMed:15901708). Also acts on L-seryl-tRNA(Ser) (PubMed:4248527).<ref>PMID:11083873</ref> <ref>PMID:12679335</ref> <ref>PMID:15901708</ref> <ref>PMID:23744707</ref> <ref>PMID:4248527</ref>
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[3gkr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Weissella_viridescens Weissella viridescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GKR OCA].
+
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gk/3gkr_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gkr ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Staphylococcus aureus]]
[[Category: Weissella viridescens]]
[[Category: Weissella viridescens]]
-
[[Category: Arthur, M.]]
+
[[Category: Arthur M]]
-
[[Category: Delfosse, V.]]
+
[[Category: Delfosse V]]
-
[[Category: Lecerf, M.]]
+
[[Category: Lecerf M]]
-
[[Category: Mayer, C.]]
+
[[Category: Mayer C]]
-
[[Category: Piton, J.]]
+
[[Category: Piton J]]
-
[[Category: Villet, R.]]
+
[[Category: Villet R]]
-
[[Category: Femx]]
+
-
[[Category: Hexapeptide]]
+
-
[[Category: Peptidoglycan]]
+
-
[[Category: Transferase]]
+

Current revision

Crystal Structure of Weissella viridescens FemX:UDP-MurNAc-hexapeptide complex

PDB ID 3gkr

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3gkr"
Personal tools