3t06
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3t06 is ON HOLD Authors: Bielnicki, J.A., Derewenda, U., Derewenda, Z.S. Description: Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-t...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-terminal regulatory elements in complex with Human RhoA== | |
| + | <StructureSection load='3t06' size='340' side='right'caption='[[3t06]], [[Resolution|resolution]] 2.84Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3t06]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T06 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.84Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t06 OCA], [https://pdbe.org/3t06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t06 RCSB], [https://www.ebi.ac.uk/pdbsum/3t06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t06 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ARHGB_HUMAN ARHGB_HUMAN] May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. | ||
| - | + | ==See Also== | |
| - | + | *[[Rho GTPase 3D structures|Rho GTPase 3D structures]] | |
| - | + | *[[Rho guanine nucleotide exchange factor 3D structures|Rho guanine nucleotide exchange factor 3D structures]] | |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bielnicki JA]] | ||
| + | [[Category: Derewenda U]] | ||
| + | [[Category: Derewenda ZS]] | ||
Current revision
Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-terminal regulatory elements in complex with Human RhoA
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