3qgp

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[[Image:3qgp.png|left|200px]]
 
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==Crystal structure of IsdI in complex with heme and cyanide==
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The line below this paragraph, containing "STRUCTURE_3qgp", creates the "Structure Box" on the page.
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<StructureSection load='3qgp' size='340' side='right'caption='[[3qgp]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3qgp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_N315 Staphylococcus aureus subsp. aureus N315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QGP FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_3qgp| PDB=3qgp | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qgp OCA], [https://pdbe.org/3qgp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qgp RCSB], [https://www.ebi.ac.uk/pdbsum/3qgp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qgp ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HDOX2_STAAN HDOX2_STAAN] Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.[HAMAP-Rule:MF_01272]<ref>PMID:18713745</ref> <ref>PMID:20180905</ref>
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===Crystal structure of IsdI in complex with heme and cyanide===
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==See Also==
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*[[Heme oxygenase 3D structures|Heme oxygenase 3D structures]]
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*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
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==About this Structure==
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== References ==
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[[3qgp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_n315 Staphylococcus aureus subsp. aureus n315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QGP OCA].
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<references/>
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[[Category: Heme oxygenase]]
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__TOC__
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[[Category: Staphylococcus aureus subsp. aureus n315]]
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</StructureSection>
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[[Category: Murphy, M E.P.]]
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[[Category: Large Structures]]
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[[Category: Ukpabi, G N.]]
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[[Category: Staphylococcus aureus subsp. aureus N315]]
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[[Category: Barrel]]
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[[Category: Murphy MEP]]
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[[Category: Dimeric alpha+beta]]
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[[Category: Ukpabi GN]]
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[[Category: Oxidoreductase]]
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Current revision

Crystal structure of IsdI in complex with heme and cyanide

PDB ID 3qgp

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