3rg6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (02:21, 21 November 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3rg6.png|left|200px]]
 
-
<!--
+
==Crystal structure of a chaperone-bound assembly intermediate of form I Rubisco==
-
The line below this paragraph, containing "STRUCTURE_3rg6", creates the "Structure Box" on the page.
+
<StructureSection load='3rg6' size='340' side='right'caption='[[3rg6]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3rg6]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Anabaena_sp. Anabaena sp.] and [https://en.wikipedia.org/wiki/Synechococcus_elongatus_PCC_6301 Synechococcus elongatus PCC 6301]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RG6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RG6 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rg6 OCA], [https://pdbe.org/3rg6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rg6 RCSB], [https://www.ebi.ac.uk/pdbsum/3rg6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rg6 ProSAT]</span></td></tr>
-
{{STRUCTURE_3rg6| PDB=3rg6 | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/RBL_SYNP6 RBL_SYNP6] RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.[HAMAP-Rule:MF_01338]
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
The form I Rubisco of autotrophic bacteria, algae and plants is a complex of eight large (RbcL) and eight small (RbcS) subunits. It fixes atmospheric CO(2) in the dark reaction of photosynthesis. As shown for the cyanobacterial enzyme, folding of the RbcL subunits is mediated by the GroEL-GroES chaperonin system, and assembly requires the specialized chaperone RbcX, a homodimer of ~15-kDa subunits. Here we present the 3.2-A crystal structure of a Rubisco assembly intermediate, consisting of the RbcL(8) core with eight RbcX(2) molecules bound. The structure reveals the molecular mechanism by which RbcX(2) mediates oligomeric assembly. Specifically, RbcX(2) provides positional information for proper formation of antiparallel RbcL dimers, thereby preventing RbcL-RbcL misalignment and off-pathway aggregation. The RbcL(8)(RbcX(2))(8) structure also suggests that RbcS functions by stabilizing the '60s loop' of RbcL in the catalytically active conformation.
-
===Crystal structure of a chaperone-bound assembly intermediate of form I Rubisco===
+
Crystal structure of a chaperone-bound assembly intermediate of form I Rubisco.,Bracher A, Starling-Windhof A, Hartl FU, Hayer-Hartl M Nat Struct Mol Biol. 2011 Jul 17. doi: 10.1038/nsmb.2090. PMID:21765418<ref>PMID:21765418</ref>
 +
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 3rg6" style="background-color:#fffaf0;"></div>
-
<!--
+
==See Also==
-
The line below this paragraph, {{ABSTRACT_PUBMED_21765418}}, adds the Publication Abstract to the page
+
*[[RuBisCO 3D structures|RuBisCO 3D structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 21765418 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_21765418}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Anabaena sp]]
-
[[3rg6]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Anabaena_sp. Anabaena sp.] and [http://en.wikipedia.org/wiki/Synechococcus_elongatus Synechococcus elongatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RG6 OCA].
+
[[Category: Large Structures]]
-
 
+
[[Category: Synechococcus elongatus PCC 6301]]
-
==Reference==
+
[[Category: Bracher A]]
-
<ref group="xtra">PMID:021765418</ref><ref group="xtra">PMID:020075914</ref><ref group="xtra">PMID:017574029</ref><ref group="xtra">PMID:015299492</ref><references group="xtra"/>
+
[[Category: Hartl FU]]
-
[[Category: Anabaena sp.]]
+
[[Category: Hayer-Hartl M]]
-
[[Category: Ribulose-bisphosphate carboxylase]]
+
[[Category: Starling-Windhof A]]
-
[[Category: Synechococcus elongatus]]
+
-
[[Category: Bracher, A.]]
+
-
[[Category: Hartl, F U.]]
+
-
[[Category: Hayer-Hartl, M.]]
+
-
[[Category: Starling-Windhof, A.]]
+
-
[[Category: Assembly chaperone]]
+
-
[[Category: Photosynthesis]]
+
-
[[Category: Protein folding]]
+

Current revision

Crystal structure of a chaperone-bound assembly intermediate of form I Rubisco

PDB ID 3rg6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3rg6"
Personal tools