3s53

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'''Unreleased structure'''
 
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The entry 3s53 is ON HOLD until Paper Publication
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==HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P212121==
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<StructureSection load='3s53' size='340' side='right'caption='[[3s53]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3s53]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S53 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S53 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=017:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE'>017</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s53 OCA], [https://pdbe.org/3s53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s53 RCSB], [https://www.ebi.ac.uk/pdbsum/3s53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s53 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q7SSI0_9HIV1 Q7SSI0_9HIV1]
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Authors: Tie, Y.-F., Wang, Y.-F., Weber, I.T.
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==See Also==
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*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
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Description: HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P212121
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__TOC__
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</StructureSection>
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[[Category: Human immunodeficiency virus 1]]
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[[Category: Large Structures]]
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[[Category: Tie Y-F]]
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[[Category: Wang Y-F]]
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[[Category: Weber IT]]

Current revision

HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P212121

PDB ID 3s53

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