3t4e
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3t4e is ON HOLD Authors: Minasov, G., Light, S.H., Halavaty, A., Shuvalova, L., Dubrovska, I. , Winsor, J. , Papazisi, L., Anderson, W.F. , Center f...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==1.95 Angstrom Crystal Structure of Shikimate 5-dehydrogenase (AroE) from Salmonella enterica subsp. enterica serovar Typhimurium in Complex with NAD== | |
| + | <StructureSection load='3t4e' size='340' side='right'caption='[[3t4e]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3t4e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T4E FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4e OCA], [https://pdbe.org/3t4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t4e RCSB], [https://www.ebi.ac.uk/pdbsum/3t4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t4e ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/YDIB_SALTY YDIB_SALTY] The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate. Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively. It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.[HAMAP-Rule:MF_01578] | ||
| - | + | ==See Also== | |
| - | + | *[[Shikimate dehydrogenase 3D structures|Shikimate dehydrogenase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium]] | ||
| + | [[Category: Anderson WF]] | ||
| + | [[Category: Dubrovska I]] | ||
| + | [[Category: Halavaty A]] | ||
| + | [[Category: Light SH]] | ||
| + | [[Category: Minasov G]] | ||
| + | [[Category: Papazisi L]] | ||
| + | [[Category: Shuvalova L]] | ||
| + | [[Category: Winsor J]] | ||
Current revision
1.95 Angstrom Crystal Structure of Shikimate 5-dehydrogenase (AroE) from Salmonella enterica subsp. enterica serovar Typhimurium in Complex with NAD
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