3t4n

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(New page: '''Unreleased structure''' The entry 3t4n is ON HOLD Authors: Mayer, F.V., Heath, R., Underwood, E., Sanders, M.J., Carmena, D., McCartney, R., Leiper, F.C., Xiao, B., Jing, C., Walker,...)
Current revision (10:02, 1 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 3t4n is ON HOLD
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==Structure of the regulatory fragment of Saccharomyces cerevisiae AMPK in complex with ADP==
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<StructureSection load='3t4n' size='340' side='right'caption='[[3t4n]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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Authors: Mayer, F.V., Heath, R., Underwood, E., Sanders, M.J., Carmena, D., McCartney, R., Leiper, F.C., Xiao, B., Jing, C., Walker, P.A., Haire, L.F., Ogrodowicz, R., Martin, S.R., Schmdit, M.C., Gamblin, S.J., Carling, D.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3t4n]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T4N FirstGlance]. <br>
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Description: STRUCTURE OF THE REGULATORY FRAGMENT OF SACCHAROMYCES CEREVISIAE AMPK IN COMPLEX WITH ADP
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4n OCA], [https://pdbe.org/3t4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t4n RCSB], [https://www.ebi.ac.uk/pdbsum/3t4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t4n ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SNF1_YEAST SNF1_YEAST] Essential for release from glucose repression. It interacts and has functional relationship to the regulatory protein SNF4. Could phosphorylate CAT8. Phosphorylates histone H3 to form H3S10ph, which promotes H3K14ac formation, and which is required for transcriptional activation through TBP recruitment to the promoters.<ref>PMID:15719021</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Carling D]]
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[[Category: Carmena D]]
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[[Category: Gamblin SJ]]
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[[Category: Haire LF]]
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[[Category: Heath R]]
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[[Category: Jing C]]
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[[Category: Leiper FC]]
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[[Category: Martin SR]]
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[[Category: Mayer FV]]
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[[Category: McCartney R]]
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[[Category: Ogrodowicz R]]
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[[Category: Sanders MJ]]
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[[Category: Schmdit MC]]
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[[Category: Underwood E]]
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[[Category: Walker PA]]
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[[Category: Xiao B]]

Current revision

Structure of the regulatory fragment of Saccharomyces cerevisiae AMPK in complex with ADP

PDB ID 3t4n

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