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3sfx

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[[Image:3sfx.jpg|left|200px]]
 
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==Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and tipifarnib==
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The line below this paragraph, containing "STRUCTURE_3sfx", creates the "Structure Box" on the page.
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<StructureSection load='3sfx' size='340' side='right'caption='[[3sfx]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3sfx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptococcus_neoformans_var._grubii_H99 Cryptococcus neoformans var. grubii H99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SFX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SFX FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3FX:(2R)-3-(CYCLOHEXYLAMINO)-2-HYDROXYPROPANE-1-SULFONIC+ACID'>3FX</scene>, <scene name='pdbligand=FII:[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC+ACID'>FII</scene>, <scene name='pdbligand=JAN:6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE'>JAN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_3sfx| PDB=3sfx | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sfx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sfx OCA], [https://pdbe.org/3sfx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sfx RCSB], [https://www.ebi.ac.uk/pdbsum/3sfx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sfx ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q55S71_CRYNB Q55S71_CRYNB]
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===Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and tipifarnib===
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==See Also==
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*[[Farnesyltransferase 3D structures|Farnesyltransferase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3sfx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryptococcus_neoformans Cryptococcus neoformans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SFX OCA].
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[[Category: Cryptococcus neoformans var. grubii H99]]
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[[Category: Cryptococcus neoformans]]
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[[Category: Large Structures]]
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[[Category: Beese, L S.]]
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[[Category: Beese LS]]
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[[Category: Hast, M A.]]
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[[Category: Hast MA]]
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[[Category: Prenyltransferase]]
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[[Category: Protein farnesyltransferase]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and tipifarnib

PDB ID 3sfx

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