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3qxy

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[[Image:3qxy.png|left|200px]]
 
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==Human SETD6 in complex with RelA Lys310==
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The line below this paragraph, containing "STRUCTURE_3qxy", creates the "Structure Box" on the page.
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<StructureSection load='3qxy' size='340' side='right'caption='[[3qxy]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3qxy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QXY FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
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{{STRUCTURE_3qxy| PDB=3qxy | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qxy OCA], [https://pdbe.org/3qxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qxy RCSB], [https://www.ebi.ac.uk/pdbsum/3qxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qxy ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SETD6_HUMAN SETD6_HUMAN] Protein-lysine N-methyltransferase that specifically monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity.<ref>PMID:21131967</ref>
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===Human SETD6 in complex with RelA Lys310===
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==See Also==
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*[[Histone methyltransferase 3D structures|Histone methyltransferase 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 21515635 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_21515635}}
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==About this Structure==
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[[3qxy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QXY OCA].
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==Reference==
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<ref group="xtra">PMID:021515635</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Chang, Y.]]
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[[Category: Large Structures]]
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[[Category: Cheng, X.]]
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[[Category: Chang Y]]
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[[Category: Gozani, O.]]
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[[Category: Cheng X]]
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[[Category: Horton, J R.]]
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[[Category: Gozani O]]
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[[Category: Levy, D.]]
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[[Category: Horton JR]]
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[[Category: Peng, J.]]
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[[Category: Levy D]]
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[[Category: Zhang, X.]]
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[[Category: Peng J]]
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[[Category: Epigenetic]]
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[[Category: Zhang X]]
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[[Category: Nf-kb network via methyllysine signaling]]
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[[Category: Protein lysine methyltransferase]]
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[[Category: Transferase]]
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Current revision

Human SETD6 in complex with RelA Lys310

PDB ID 3qxy

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OCA

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