3t7h

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m (Protected "3t7h" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 3t7h is ON HOLD
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==Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway==
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<StructureSection load='3t7h' size='340' side='right'caption='[[3t7h]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3t7h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T7H FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t7h OCA], [https://pdbe.org/3t7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t7h RCSB], [https://www.ebi.ac.uk/pdbsum/3t7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t7h ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ATG7_YEAST ATG7_YEAST] E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.<ref>PMID:9759731</ref> <ref>PMID:8224160</ref> <ref>PMID:7593182</ref> <ref>PMID:10233148</ref> <ref>PMID:10233150</ref> <ref>PMID:11100732</ref> <ref>PMID:11149920</ref> <ref>PMID:12965207</ref> <ref>PMID:15277523</ref>
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Authors: Taherbhoy, A.M., Tait, S.W., Kaiser, S.E., Williams, A.H., Deng, A., Nourse, A., Hammel, M., Kurinov, I., Rock, C.O., Green, D.R., Schulman, B.A.
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==See Also==
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*[[Autophagy-related protein 3D structures|Autophagy-related protein 3D structures]]
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Description: E1 Domain Mut
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Deng A]]
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[[Category: Green DR]]
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[[Category: Hammel M]]
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[[Category: Kaiser SE]]
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[[Category: Kurinov I]]
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[[Category: Nourse A]]
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[[Category: Rock CO]]
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[[Category: Schulman BA]]
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[[Category: Taherbhoy AM]]
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[[Category: Tait SW]]
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[[Category: Williams AH]]

Current revision

Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway

PDB ID 3t7h

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