3t7l

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m (Protected "3t7l" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 3t7l is ON HOLD
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==Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution==
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<StructureSection load='3t7l' size='340' side='right'caption='[[3t7l]], [[Resolution|resolution]] 1.09&Aring;' scene=''>
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Authors: Chaikuad, A., Williams, E., Guo, K., Sanvitale, C., Berridge, G., Krojer, T., Muniz, J.R.C., Canning, P., Phillips, C., Shrestha, A., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3t7l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T7L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T7L FirstGlance]. <br>
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Description: Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.09&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t7l OCA], [https://pdbe.org/3t7l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t7l RCSB], [https://www.ebi.ac.uk/pdbsum/3t7l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t7l ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ZFY16_HUMAN ZFY16_HUMAN] May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.<ref>PMID:11546807</ref> <ref>PMID:14613930</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith CH]]
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[[Category: Berridge G]]
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[[Category: Bountra C]]
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[[Category: Bullock A]]
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[[Category: Canning P]]
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[[Category: Chaikuad A]]
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[[Category: Edwards AM]]
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[[Category: Guo K]]
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[[Category: Krojer T]]
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[[Category: Muniz JRC]]
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[[Category: Phillips C]]
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[[Category: Sanvitale C]]
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[[Category: Shrestha A]]
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[[Category: Weigelt J]]
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[[Category: Williams E]]
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[[Category: Von Delft F]]

Current revision

Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution

PDB ID 3t7l

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