3t8x
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3t8x is ON HOLD Authors: Garcia-Alles, L.F., Maveyraud, L., Mourey, L., Julien, S. Description: Crystal structure of human CD1b in complex with syn...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human CD1b in complex with synthetic antigenic diacylsulfoglycolipid SGL12 and endogenous spacer== | |
| + | <StructureSection load='3t8x' size='340' side='right'caption='[[3t8x]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3t8x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T8X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T8X FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=T8X:2-O-SULFO-ALPHA-D-GLUCOPYRANOSYL+2-O-HEXADECANOYL-3-O-[(2E,4S,6S,8S)-2,4,6,8-TETRAMETHYLTETRACOS-2-ENOYL]-ALPHA-D-GLUCOPYRANOSIDE'>T8X</scene>, <scene name='pdbligand=ULI:TETRACONTANE'>ULI</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t8x OCA], [https://pdbe.org/3t8x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t8x RCSB], [https://www.ebi.ac.uk/pdbsum/3t8x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t8x ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CD1B_HUMAN CD1B_HUMAN] Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.<ref>PMID:10981968</ref> <ref>PMID:14716313</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]] | |
| - | + | *[[CD1|CD1]] | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Garcia-Alles LF]] | ||
| + | [[Category: Julien S]] | ||
| + | [[Category: Maveyraud L]] | ||
| + | [[Category: Mourey L]] | ||
Current revision
Crystal structure of human CD1b in complex with synthetic antigenic diacylsulfoglycolipid SGL12 and endogenous spacer
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