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3ta8
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3ta8 is ON HOLD Authors: Tsuruta, O., Yokoyama, H., Fujii S. Description: Crystal structure HP-NAP from strain YS39 iron loaded (cocrystallization ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure HP-NAP from strain YS39 iron loaded (cocrystallization 5mM)== | |
| + | <StructureSection load='3ta8' size='340' side='right'caption='[[3ta8]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3ta8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TA8 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ta8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ta8 OCA], [https://pdbe.org/3ta8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ta8 RCSB], [https://www.ebi.ac.uk/pdbsum/3ta8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ta8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/G1UIZ3_HELPX G1UIZ3_HELPX] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | A new crystal lattice structure of Helicobacter pylori neutrophil-activating protein (HP-NAP) has been determined in two forms: the native state (Apo) at 2.20 A resolution and an iron-loaded form (Fe-load) at 2.50 A resolution. The highly solvated packing of the dodecameric shell is suitable for crystallographic study of the metal ion-uptake pathway. Like other bacterioferritins, HP-NAP forms a spherical dodecamer with 23 symmetry including two kinds of channels. Iron loading causes a series of conformational changes of amino-acid residues (Trp26, Asp52 and Glu56) at the ferroxidase centre. | ||
| - | + | A new crystal lattice structure of Helicobacter pylori neutrophil-activating protein (HP-NAP).,Tsuruta O, Yokoyama H, Fujii S Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1;68(Pt 2):134-40., Epub 2012 Jan 25. PMID:22297984<ref>PMID:22297984</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| + | </div> | ||
| + | <div class="pdbe-citations 3ta8" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Helicobacter pylori]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fujii S]] | ||
| + | [[Category: Tsuruta O]] | ||
| + | [[Category: Yokoyama H]] | ||
Current revision
Crystal structure HP-NAP from strain YS39 iron loaded (cocrystallization 5mM)
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