2pbf

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(New page: 200px<br /><applet load="2pbf" size="350" color="white" frame="true" align="right" spinBox="true" caption="2pbf, resolution 2.00&Aring;" /> '''Crystal structure of...)
Current revision (10:58, 30 August 2023) (edit) (undo)
 
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[[Image:2pbf.gif|left|200px]]<br /><applet load="2pbf" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2pbf, resolution 2.00&Aring;" />
 
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'''Crystal structure of a putative protein-L-isoaspartate O-methyltransferase beta-aspartate methyltransferase (PCMT) from Plasmodium falciparum in complex with S-adenosyl-L-homocysteine'''<br />
 
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==About this Structure==
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==Crystal structure of a putative protein-L-isoaspartate O-methyltransferase beta-aspartate methyltransferase (PCMT) from Plasmodium falciparum in complex with S-adenosyl-L-homocysteine==
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2PBF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_3d7 Plasmodium falciparum 3d7] with <scene name='pdbligand=SAH:'>SAH</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Protein-L-isoaspartate(D-aspartate)_O-methyltransferase Protein-L-isoaspartate(D-aspartate) O-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.77 2.1.1.77] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PBF OCA].
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<StructureSection load='2pbf' size='340' side='right'caption='[[2pbf]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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[[Category: Plasmodium falciparum 3d7]]
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== Structural highlights ==
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[[Category: Protein-L-isoaspartate(D-aspartate) O-methyltransferase]]
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<table><tr><td colspan='2'>[[2pbf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PBF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PBF FirstGlance]. <br>
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[[Category: Single protein]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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[[Category: Arrowsmith, C.H.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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[[Category: Bochkarev, A.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pbf OCA], [https://pdbe.org/2pbf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pbf RCSB], [https://www.ebi.ac.uk/pdbsum/2pbf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pbf ProSAT]</span></td></tr>
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[[Category: Edwards, A.M.]]
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</table>
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[[Category: Hassanali, A.]]
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== Evolutionary Conservation ==
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[[Category: Hui, R.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Kozieradzki, I.]]
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Check<jmol>
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[[Category: Lew, J.]]
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<jmolCheckbox>
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[[Category: Lin, L.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pb/2pbf_consurf.spt"</scriptWhenChecked>
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[[Category: Qiu, W.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Ravichandran, M.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: SGC, Structural.Genomics.Consortium.]]
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</jmolCheckbox>
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[[Category: Sundstrom, M.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pbf ConSurf].
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[[Category: Vedadi, M.]]
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<div style="clear:both"></div>
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[[Category: Wasney, G.]]
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__TOC__
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[[Category: Weigelt, J.]]
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</StructureSection>
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[[Category: Wernimont, A.K.]]
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[[Category: Large Structures]]
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[[Category: Zhao, Y.]]
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[[Category: Plasmodium falciparum 3D7]]
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[[Category: SAH]]
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[[Category: Arrowsmith CH]]
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[[Category: isoaspartyl formation]]
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[[Category: Bochkarev A]]
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[[Category: methyltransferase]]
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[[Category: Edwards AM]]
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[[Category: p. falciparum]]
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[[Category: Hassanali A]]
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[[Category: protein repair]]
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[[Category: Hui R]]
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[[Category: sgc]]
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[[Category: Kozieradzki I]]
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[[Category: structural genomics consortium]]
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[[Category: Lew J]]
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[[Category: Lin L]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 21:22:03 2008''
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[[Category: Qiu W]]
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[[Category: Ravichandran M]]
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[[Category: Sundstrom M]]
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[[Category: Vedadi M]]
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[[Category: Wasney G]]
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[[Category: Weigelt J]]
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[[Category: Wernimont AK]]
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[[Category: Zhao Y]]

Current revision

Crystal structure of a putative protein-L-isoaspartate O-methyltransferase beta-aspartate methyltransferase (PCMT) from Plasmodium falciparum in complex with S-adenosyl-L-homocysteine

PDB ID 2pbf

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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