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354d

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(New page: 200px<br /><applet load="354d" size="350" color="white" frame="true" align="right" spinBox="true" caption="354d, resolution 1.500&Aring;" /> '''STRUCTURE OF LOOP E...)
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[[Image:354d.jpg|left|200px]]<br /><applet load="354d" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="354d, resolution 1.500&Aring;" />
 
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'''STRUCTURE OF LOOP E FROM E. COLI 5S RRNA'''<br />
 
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==Overview==
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==Structure of loop E FROM E. coli 5S RRNA==
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Two new RNA structures portray how non-Watson-Crick base pairs and metal, ions can produce a unique RNA shape suitable for recognition by proteins., The crystal structures of a 62 nt domain of E. coli 5S ribosomal RNA and a, duplex dodecamer encompassing an internal loop E have been determined at, 3.0 and 1.5 A, respectively. This loop E region is distorted by three, "cross-strand purine stacks" and three novel, water-mediated noncanonical, base pairs and stabilized by a four metal ion zipper. These features give, its minor groove a unique hydrogen-bonding surface and make the adjacent, major groove wide enough to permit recognition by the ribosomal protein, L25, which is expected to bind to this surface.
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<StructureSection load='354d' size='340' side='right'caption='[[354d]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[354d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=354D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=354D FirstGlance]. <br>
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354D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=S:'>S</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=354D OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G46:GUANOSINE-5-MONOTHIOPHOSPHATE'>G46</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=354d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=354d OCA], [https://pdbe.org/354d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=354d RCSB], [https://www.ebi.ac.uk/pdbsum/354d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=354d ProSAT]</span></td></tr>
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Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain., Correll CC, Freeborn B, Moore PB, Steitz TA, Cell. 1997 Nov 28;91(5):705-12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9393863 9393863]
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</table>
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[[Category: ]]
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__TOC__
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[[Category: Protein complex]]
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</StructureSection>
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[[Category: Correll, C.C.]]
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[[Category: Escherichia coli]]
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[[Category: Freeborn, B.]]
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[[Category: Large Structures]]
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[[Category: Moore, P.B.]]
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[[Category: Correll CC]]
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[[Category: Steitz, T.A.]]
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[[Category: Freeborn B]]
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[[Category: MG]]
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[[Category: Moore PB]]
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[[Category: S]]
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[[Category: Steitz TA]]
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[[Category: double helix]]
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[[Category: internal loop]]
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[[Category: mismatched]]
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[[Category: overhanging base]]
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[[Category: u-rna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 21:36:24 2008''
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Current revision

Structure of loop E FROM E. coli 5S RRNA

PDB ID 354d

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