3t4e

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[[Image:3t4e.jpg|left|200px]]
 
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==1.95 Angstrom Crystal Structure of Shikimate 5-dehydrogenase (AroE) from Salmonella enterica subsp. enterica serovar Typhimurium in Complex with NAD==
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The line below this paragraph, containing "STRUCTURE_3t4e", creates the "Structure Box" on the page.
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<StructureSection load='3t4e' size='340' side='right'caption='[[3t4e]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3t4e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T4E FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_3t4e| PDB=3t4e | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4e OCA], [https://pdbe.org/3t4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t4e RCSB], [https://www.ebi.ac.uk/pdbsum/3t4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t4e ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/YDIB_SALTY YDIB_SALTY] The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate. Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively. It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.[HAMAP-Rule:MF_01578]
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===1.95 Angstrom Crystal Structure of Shikimate 5-dehydrogenase (AroE) from Salmonella enterica subsp. enterica serovar Typhimurium in Complex with NAD===
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==See Also==
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*[[Shikimate dehydrogenase 3D structures|Shikimate dehydrogenase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3t4e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4E OCA].
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[[Category: Large Structures]]
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[[Category: Quinate/shikimate dehydrogenase]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
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[[Category: Anderson WF]]
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[[Category: Anderson, W F.]]
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[[Category: Dubrovska I]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Halavaty A]]
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[[Category: Dubrovska, I.]]
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[[Category: Light SH]]
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[[Category: Halavaty, A.]]
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[[Category: Minasov G]]
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[[Category: Light, S H.]]
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[[Category: Papazisi L]]
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[[Category: Minasov, G.]]
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[[Category: Shuvalova L]]
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[[Category: Papazisi, L.]]
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[[Category: Winsor J]]
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[[Category: Shuvalova, L.]]
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[[Category: Winsor, J.]]
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[[Category: Aminoacid dehydrogenase-like n-terminal domain]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Csgid]]
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[[Category: Nad]]
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[[Category: Oxidoreductase]]
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[[Category: Structural genomic]]
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Current revision

1.95 Angstrom Crystal Structure of Shikimate 5-dehydrogenase (AroE) from Salmonella enterica subsp. enterica serovar Typhimurium in Complex with NAD

PDB ID 3t4e

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