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3tav

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[[Image:3tav.jpg|left|200px]]
 
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==Crystal structure of a Methionine Aminopeptidase from Mycobacterium abscessus==
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The line below this paragraph, containing "STRUCTURE_3tav", creates the "Structure Box" on the page.
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<StructureSection load='3tav' size='340' side='right'caption='[[3tav]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3tav]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacteroides_abscessus_ATCC_19977 Mycobacteroides abscessus ATCC 19977]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TAV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TAV FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMR:(2S)-2-HYDROXYBUTANEDIOIC+ACID'>LMR</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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{{STRUCTURE_3tav| PDB=3tav | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tav FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tav OCA], [https://pdbe.org/3tav PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tav RCSB], [https://www.ebi.ac.uk/pdbsum/3tav PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tav ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/B1MGB2_MYCA9 B1MGB2_MYCA9] Removes the N-terminal methionine from nascent proteins.[RuleBase:RU003653] Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.[HAMAP-Rule:MF_01974]
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===Crystal structure of a Methionine Aminopeptidase from Mycobacterium abscessus===
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==See Also==
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3tav]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_abscessus Mycobacterium abscessus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TAV OCA].
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[[Category: Large Structures]]
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[[Category: Methionyl aminopeptidase]]
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[[Category: Mycobacteroides abscessus ATCC 19977]]
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[[Category: Mycobacterium abscessus]]
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[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
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[[Category: Auto-catalytic removal of tag]]
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[[Category: Cobalt binding]]
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[[Category: Hydrolase]]
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[[Category: M24a family]]
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[[Category: Metalloexopeptidase]]
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[[Category: No anomalous signal indicates magnesium ions in active site]]
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[[Category: Protease]]
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[[Category: Seattle structural genomics center for infectious disease]]
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[[Category: Ssgcid]]
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Current revision

Crystal structure of a Methionine Aminopeptidase from Mycobacterium abscessus

PDB ID 3tav

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