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3lkf

From Proteopedia

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[[Image:3lkf.png|left|200px]]
 
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==LEUKOCIDIN F (HLGB) FROM STAPHYLOCOCCUS AUREUS WITH PHOSPHOCHOLINE BOUND==
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The line below this paragraph, containing "STRUCTURE_3lkf", creates the "Structure Box" on the page.
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<StructureSection load='3lkf' size='340' side='right'caption='[[3lkf]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3lkf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LKF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene></td></tr>
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{{STRUCTURE_3lkf| PDB=3lkf | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lkf OCA], [https://pdbe.org/3lkf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lkf RCSB], [https://www.ebi.ac.uk/pdbsum/3lkf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lkf ProSAT]</span></td></tr>
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</table>
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===LEUKOCIDIN F (HLGB) FROM STAPHYLOCOCCUS AUREUS WITH PHOSPHOCHOLINE BOUND===
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== Function ==
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[https://www.uniprot.org/uniprot/HLGB_STAAU HLGB_STAAU] Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity.
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_10048924}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 10048924 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lk/3lkf_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_10048924}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[3lkf]] is a 1 chain structure of [[Pore forming toxin%2C α-hemolysin]] with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LKF OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lkf ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Pore forming toxin%2C α-hemolysin]]
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*[[Pore forming toxin%2C α-hemolysin|Pore forming toxin%2C α-hemolysin]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:010048924</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Gouaux, J E.]]
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[[Category: Gouaux JE]]
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[[Category: Kamio, Y.]]
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[[Category: Kamio Y]]
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[[Category: Nariya, H.]]
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[[Category: Nariya H]]
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[[Category: Olson, R.]]
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[[Category: Olson R]]
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[[Category: Yokota, K.]]
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[[Category: Yokota K]]
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[[Category: Hemolysin]]
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[[Category: Leukotoxin]]
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[[Category: Pore-forming toxin]]
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[[Category: Toxin]]
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Current revision

LEUKOCIDIN F (HLGB) FROM STAPHYLOCOCCUS AUREUS WITH PHOSPHOCHOLINE BOUND

PDB ID 3lkf

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