2wjn

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[[Image:2wjn.png|left|200px]]
 
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==Lipidic sponge phase crystal structure of photosynthetic reaction centre from Blastochloris viridis (high dose)==
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The line below this paragraph, containing "STRUCTURE_2wjn", creates the "Structure Box" on the page.
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<StructureSection load='2wjn' size='340' side='right'caption='[[2wjn]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2wjn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Blastochloris_viridis Blastochloris viridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WJN FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BPB:BACTERIOPHEOPHYTIN+B'>BPB</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=FME:N-FORMYLMETHIONINE'>FME</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=MPG:[(Z)-OCTADEC-9-ENYL]+(2R)-2,3-BIS(OXIDANYL)PROPANOATE'>MPG</scene>, <scene name='pdbligand=MQ7:MENAQUINONE-7'>MQ7</scene>, <scene name='pdbligand=NS5:15-CIS-1,2-DIHYDRONEUROSPORENE'>NS5</scene></td></tr>
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{{STRUCTURE_2wjn| PDB=2wjn | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjn OCA], [https://pdbe.org/2wjn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wjn RCSB], [https://www.ebi.ac.uk/pdbsum/2wjn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wjn ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CYCR_BLAVI CYCR_BLAVI] The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor.<ref>PMID:10736158</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wj/2wjn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wjn ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Membrane proteins are embedded in a lipid bilayer and maintain strong interactions with lipid molecules. Tightly bound lipids are responsible for vertical positioning and integration of proteins in the membrane, for assembly of multisubunit complexes, and occasionally act as substrates. In this work we present the lipidic-sponge phase crystal structure of the reaction center from Blastochloris viridis to 1.86 A, which reveals lipid molecules interacting with the protein surface. A diacylglycerol molecule is bound, through a thioether bond, to the N-terminus of the tetraheme cytochrome c subunit. From the electron density recovered at the QB site and the observed change in recombination kinetics in lipidic sponge phase grown crystals, the mobile ubiquinone appears to be displaced by a monoolein molecule. A 36 A long electron density feature is observed at the interface of transmembrane helices belonging to the H- and M-subunits, probably arising from an unidentified lipid.
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===LIPIDIC SPONGE PHASE CRYSTAL STRUCTURE OF PHOTOSYNTHETIC REACTION CENTRE FROM BLASTOCHLORIS VIRIDIS (HIGH DOSE)===
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Lipidic-sponge phase crystal structure of a photosynthetic reaction center reveals lipids on the protein surface.,Wohri AB, Wahlgren WY, Malmerberg E, Johansson LC, Neutze R, Katona G Biochemistry. 2009 Sep 10. PMID:19743880<ref>PMID:19743880</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_19743880}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 2wjn" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 19743880 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19743880}}
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==About this Structure==
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[[2wjn]] is a 4 chain structure of [[Cytochrome c]] with sequence from [http://en.wikipedia.org/wiki/Blastochloris_viridis Blastochloris viridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJN OCA].
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==See Also==
==See Also==
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*[[Cytochrome c]]
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*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:019743880</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Blastochloris viridis]]
[[Category: Blastochloris viridis]]
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[[Category: Johansson, L C.]]
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[[Category: Large Structures]]
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[[Category: Katona, G.]]
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[[Category: Johansson LC]]
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[[Category: Malmerberg, E.]]
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[[Category: Katona G]]
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[[Category: Neutze, R.]]
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[[Category: Malmerberg E]]
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[[Category: Wahlgren, W Y.]]
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[[Category: Neutze R]]
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[[Category: Wohri, A B.]]
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[[Category: Wahlgren WY]]
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[[Category: Bacteriochlorophyll]]
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[[Category: Wohri AB]]
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[[Category: Cell membrane]]
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[[Category: Chlorophyll]]
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[[Category: Chromophore]]
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[[Category: Electron transport]]
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[[Category: Formylation]]
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[[Category: Heme]]
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[[Category: Iron]]
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[[Category: Lipidic-sponge phase]]
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[[Category: Lipid]]
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[[Category: Lipoprotein]]
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[[Category: Magnesium]]
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[[Category: Membrane]]
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[[Category: Metal-binding]]
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[[Category: Photosynthesis]]
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[[Category: Reaction center]]
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[[Category: Transmembrane]]
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[[Category: Transport]]
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Current revision

Lipidic sponge phase crystal structure of photosynthetic reaction centre from Blastochloris viridis (high dose)

PDB ID 2wjn

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