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2cd9

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[[Image:2cd9.png|left|200px]]
 
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==Sulfolobus solfataricus Glucose Dehydrogenase 1 - apo form==
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The line below this paragraph, containing "STRUCTURE_2cd9", creates the "Structure Box" on the page.
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<StructureSection load='2cd9' size='340' side='right'caption='[[2cd9]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2cd9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CD9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CD9 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_2cd9| PDB=2cd9 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cd9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cd9 OCA], [https://pdbe.org/2cd9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cd9 RCSB], [https://www.ebi.ac.uk/pdbsum/2cd9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cd9 ProSAT]</span></td></tr>
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</table>
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===SULFOLOBUS SOLFATARICUS GLUCOSE DEHYDROGENASE 1 - APO FORM===
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== Function ==
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[https://www.uniprot.org/uniprot/GLCDH_SACSO GLCDH_SACSO] Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Displays broad substrate specificity since it is able to catalyze the oxidation of a number of alternative aldose sugars, such as D-galactose, D-xylose and L-arabinose, to the corresponding glyconate. Can utilize both NAD(+) and NADP(+) as electron acceptor. Physiologically, seems to be involved in the degradation of both glucose and galactose through a non-phosphorylative variant of the Entner-Doudoroff pathway.<ref>PMID:12824170</ref> <ref>PMID:3827812</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_16556607}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 16556607 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cd/2cd9_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_16556607}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[2cd9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CD9 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cd9 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:016556607</ref><references group="xtra"/>
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<references/>
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[[Category: Glucose 1-dehydrogenase]]
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__TOC__
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[[Category: Sulfolobus solfataricus]]
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</StructureSection>
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[[Category: Danson, M J.]]
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[[Category: Large Structures]]
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[[Category: Hough, D W.]]
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[[Category: Saccharolobus solfataricus]]
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[[Category: Lamble, H J.]]
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[[Category: Danson MJ]]
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[[Category: Milburn, C C.]]
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[[Category: Hough DW]]
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[[Category: Taylor, G L.]]
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[[Category: Lamble HJ]]
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[[Category: Theodossis, A.]]
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[[Category: Milburn CC]]
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[[Category: Glucose dehydrogenase]]
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[[Category: Taylor GL]]
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[[Category: Medium chain dehydrogenase family]]
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[[Category: Theodossis A]]
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[[Category: Oxidoreductase]]
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Current revision

Sulfolobus solfataricus Glucose Dehydrogenase 1 - apo form

PDB ID 2cd9

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