2v5f
From Proteopedia
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| - | [[Image:2v5f.png|left|200px]] | ||
| - | + | ==Crystal structure of wild type peptide-binding domain of human type I collagen prolyl 4-hydroxylase.== | |
| - | + | <StructureSection load='2v5f' size='340' side='right'caption='[[2v5f]], [[Resolution|resolution]] 2.03Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2v5f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V5F FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03Å</td></tr> | |
| - | --> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v5f OCA], [https://pdbe.org/2v5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v5f RCSB], [https://www.ebi.ac.uk/pdbsum/2v5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v5f ProSAT]</span></td></tr> |
| - | + | </table> | |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/P4HA1_HUMAN P4HA1_HUMAN] Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v5/2v5f_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v5f ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Hydroxylases 3D structures|Hydroxylases 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | [[ | + | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Hieta | + | [[Category: Synthetic construct]] |
| - | [[Category: Kivirikko | + | [[Category: Hieta R]] |
| - | [[Category: Myllyharju | + | [[Category: Kivirikko K]] |
| - | [[Category: Pekkala | + | [[Category: Myllyharju J]] |
| - | [[Category: Wierenga | + | [[Category: Pekkala M]] |
| - | + | [[Category: Wierenga R]] | |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of wild type peptide-binding domain of human type I collagen prolyl 4-hydroxylase.
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