3tcx

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'''Unreleased structure'''
 
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The entry 3tcx is ON HOLD
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==Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation==
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<StructureSection load='3tcx' size='340' side='right'caption='[[3tcx]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3tcx]] is a 28 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TCX FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tcx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tcx OCA], [https://pdbe.org/3tcx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tcx RCSB], [https://www.ebi.ac.uk/pdbsum/3tcx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tcx ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ITAL_HUMAN ITAL_HUMAN] Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
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Authors: Kang, S., Kim, C.U., Gu, X., Owens, R.M., van Rijn, S.J., Boonyaleepun, V., Mao, Y., Springer, T.A., Jin, M.M.
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==See Also==
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*[[Integrin 3D structures|Integrin 3D structures]]
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Description: Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation
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*[[Intercellular adhesion molecule|Intercellular adhesion molecule]]
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Boonyaleepun V]]
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[[Category: Gu X]]
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[[Category: Jin MM]]
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[[Category: Kang S]]
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[[Category: Kim CU]]
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[[Category: Mao Y]]
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[[Category: Owens RM]]
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[[Category: Springer TA]]
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[[Category: Van Rijn SJ]]

Current revision

Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation

PDB ID 3tcx

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