3tem
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3tem is ON HOLD Authors: Dunstan, M.S., Leys, D. Description: Quinone Oxidoreductase (NQ02) bound to the imidazoacridin-6-one 6a1) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Quinone Oxidoreductase (NQ02) bound to the imidazoacridin-6-one 6a1== | |
| + | <StructureSection load='3tem' size='340' side='right'caption='[[3tem]], [[Resolution|resolution]] 1.45Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3tem]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TEM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TEM FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6A1:HYDROXY(2-{[(5S)-6-HYDROXY-8-METHOXY-4,5-DIHYDRO-3H-IMIDAZO[4,5,1-DE]ACRIDIN-5-YL]AMINO}ETHYL)DIMETHYLAMMONIUM'>6A1</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tem OCA], [https://pdbe.org/3tem PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tem RCSB], [https://www.ebi.ac.uk/pdbsum/3tem PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tem ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Quinone reductase 3D structures|Quinone reductase 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Dunstan MS]] | ||
| + | [[Category: Leys D]] | ||
Current revision
Quinone Oxidoreductase (NQ02) bound to the imidazoacridin-6-one 6a1
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