3tex
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3tex is ON HOLD until Paper Publication Authors: Feld, G.K., Krantz, B.A. Description: Crystal Structure of Anthrax Protective Antigen (Membrane In...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) to 1.7-A resolution== | |
| - | + | <StructureSection load='3tex' size='340' side='right'caption='[[3tex]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3tex]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TEX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tex OCA], [https://pdbe.org/3tex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tex RCSB], [https://www.ebi.ac.uk/pdbsum/3tex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tex ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PAG_BACAN PAG_BACAN] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bacillus anthracis]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Feld GK]] | ||
| + | [[Category: Krantz BA]] | ||
Current revision
Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) to 1.7-A resolution
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