2yc5

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[[Image:2yc5.jpg|left|200px]]
 
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==Inhibitors of the herbicidal target IspD==
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The line below this paragraph, containing "STRUCTURE_2yc5", creates the "Structure Box" on the page.
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<StructureSection load='2yc5' size='340' side='right'caption='[[2yc5]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2yc5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YC5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YC5 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6BC:5-CHLORO-7-HYDROXY-6-(PHENYLMETHYL)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBONITRILE'>6BC</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_2yc5| PDB=2yc5 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yc5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yc5 OCA], [https://pdbe.org/2yc5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yc5 RCSB], [https://www.ebi.ac.uk/pdbsum/2yc5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yc5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ISPD_ARATH ISPD_ARATH] Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Is essential for chloroplast development and required for pigments and gibberellins biosynthesis.<ref>PMID:10841550</ref> <ref>PMID:12029484</ref> <ref>PMID:18236010</ref>
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===INHIBITORS OF THE HERBICIDAL TARGET ISPD===
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==See Also==
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*[[MEP cytidylyltransferase 3D structures|MEP cytidylyltransferase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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[[2yc5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YC5 OCA].
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__TOC__
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:021766403</ref><ref group="xtra">PMID:016478479</ref><references group="xtra"/>
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[[Category: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase]]
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[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
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[[Category: Hoeffken, H W.]]
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[[Category: Large Structures]]
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[[Category: Allosteric pocket]]
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[[Category: Hoeffken HW]]
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[[Category: Herbicide]]
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[[Category: Non-mevalonate-pathway]]
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[[Category: Transferase]]
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Current revision

Inhibitors of the herbicidal target IspD

PDB ID 2yc5

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