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3p4j

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[[Image:3p4j.jpg|left|200px]]
 
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==Ultra-high resolution structure of d(CGCGCG)2 Z-DNA==
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The line below this paragraph, containing "STRUCTURE_3p4j", creates the "Structure Box" on the page.
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<StructureSection load='3p4j' size='340' side='right'caption='[[3p4j]], [[Resolution|resolution]] 0.55&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3p4j]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P4J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P4J FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.55&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
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{{STRUCTURE_3p4j| PDB=3p4j | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p4j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p4j OCA], [https://pdbe.org/3p4j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p4j RCSB], [https://www.ebi.ac.uk/pdbsum/3p4j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p4j ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structure of a Z-DNA hexamer duplex d(CGCGCG)(2) determined at ultra high resolution of 0.55 A and refined without restraints, displays a high degree of regularity and rigidity in its stereochemistry, in contrast to the more flexible B-DNA duplexes. The estimations of standard uncertainties of all individually refined parameters, obtained by full-matrix least-squares optimization, are comparable with values that are typical for small-molecule crystallography. The Z-DNA model generated with ultra high-resolution diffraction data can be used to revise the stereochemical restraints applied in lower resolution refinements. Detailed comparisons of the stereochemical library values with the present accurate Z-DNA parameters, shows in general a good agreement, but also reveals significant discrepancies in the description of guanine-sugar valence angles and in the geometry of the phosphate groups.
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===Ultra-high resolution structure of d(CGCGCG)2 Z-DNA===
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High regularity of Z-DNA revealed by ultra high-resolution crystal structure at 0.55 A.,Brzezinski K, Brzuszkiewicz A, Dauter M, Kubicki M, Jaskolski M, Dauter Z Nucleic Acids Res. 2011 Aug 1;39(14):6238-48. Epub 2011 Apr 1. PMID:21459852<ref>PMID:21459852</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3p4j" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_21459852}}, adds the Publication Abstract to the page
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*[[Z-DNA|Z-DNA]]
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(as it appears on PubMed at http://www.pubmed.gov), where 21459852 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_21459852}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[3p4j]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P4J OCA].
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[[Category: Brzezinski K]]
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[[Category: Brzuszkiewicz A]]
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==Reference==
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[[Category: Dauter M]]
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<ref group="xtra">PMID:021459852</ref><references group="xtra"/>
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[[Category: Dauter Z]]
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[[Category: Brzezinski, K.]]
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[[Category: Jaskolski M]]
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[[Category: Brzuszkiewicz, A.]]
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[[Category: Kubicki M]]
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[[Category: Dauter, M.]]
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[[Category: Dauter, Z.]]
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[[Category: Jaskolski, M.]]
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[[Category: Kubicki, M.]]
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[[Category: Dna]]
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[[Category: Z-dna]]
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Current revision

Ultra-high resolution structure of d(CGCGCG)2 Z-DNA

PDB ID 3p4j

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