2uz9
From Proteopedia
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| - | [[Image:2uz9.jpg|left|200px]]<br /><applet load="2uz9" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2uz9, resolution 2.30Å" /> | ||
| - | '''HUMAN GUANINE DEAMINASE (GUAD) IN COMPLEX WITH ZINC AND ITS PRODUCT XANTHINE.'''<br /> | ||
| - | == | + | ==Human guanine deaminase (guaD) in complex with zinc and its product Xanthine.== |
| - | + | <StructureSection load='2uz9' size='340' side='right'caption='[[2uz9]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2uz9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UZ9 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XAN:XANTHINE'>XAN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uz9 OCA], [https://pdbe.org/2uz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uz9 RCSB], [https://www.ebi.ac.uk/pdbsum/2uz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uz9 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GUAD_HUMAN GUAD_HUMAN] Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uz/2uz9_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2uz9 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Deaminase 3D structures|Deaminase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith C]] |
| - | [[Category: Berglund | + | [[Category: Berglund H]] |
| - | [[Category: Busam | + | [[Category: Busam R]] |
| - | [[Category: Collins | + | [[Category: Collins R]] |
| - | [[Category: Dahlgren | + | [[Category: Dahlgren LG]] |
| - | [[Category: Edwards | + | [[Category: Edwards A]] |
| - | [[Category: Flodin | + | [[Category: Flodin S]] |
| - | [[Category: Flores | + | [[Category: Flores A]] |
| - | [[Category: Graslund | + | [[Category: Graslund S]] |
| - | [[Category: Hallberg | + | [[Category: Hallberg BM]] |
| - | [[Category: Hammarstrom | + | [[Category: Hammarstrom M]] |
| - | [[Category: Holmberg-Schiavone | + | [[Category: Holmberg-Schiavone L]] |
| - | [[Category: Johansson | + | [[Category: Johansson I]] |
| - | [[Category: Kallas | + | [[Category: Kallas A]] |
| - | [[Category: Karlberg | + | [[Category: Karlberg T]] |
| - | [[Category: Kotenyova | + | [[Category: Kotenyova T]] |
| - | [[Category: Lehtio | + | [[Category: Lehtio L]] |
| - | [[Category: Moche | + | [[Category: Moche M]] |
| - | [[Category: Nordlund | + | [[Category: Nordlund P]] |
| - | [[Category: Nyman | + | [[Category: Nyman T]] |
| - | [[Category: Ogg | + | [[Category: Ogg D]] |
| - | [[Category: Persson | + | [[Category: Persson C]] |
| - | [[Category: Sagemark | + | [[Category: Sagemark J]] |
| - | + | [[Category: Stenmark P]] | |
| - | [[Category: Stenmark | + | [[Category: Sundstrom M]] |
| - | [[Category: Sundstrom | + | [[Category: Thorsell AG]] |
| - | [[Category: Thorsell | + | [[Category: Weigelt J]] |
| - | + | [[Category: Welin M]] | |
| - | [[Category: Weigelt | + | [[Category: Van den berg S]] |
| - | [[Category: Welin | + | |
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Current revision
Human guanine deaminase (guaD) in complex with zinc and its product Xanthine.
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Categories: Homo sapiens | Large Structures | Arrowsmith C | Berglund H | Busam R | Collins R | Dahlgren LG | Edwards A | Flodin S | Flores A | Graslund S | Hallberg BM | Hammarstrom M | Holmberg-Schiavone L | Johansson I | Kallas A | Karlberg T | Kotenyova T | Lehtio L | Moche M | Nordlund P | Nyman T | Ogg D | Persson C | Sagemark J | Stenmark P | Sundstrom M | Thorsell AG | Weigelt J | Welin M | Van den berg S
