1a0e

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[[Image:1a0e.gif|left|200px]]<br /><applet load="1a0e" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1a0e, resolution 2.7&Aring;" />
 
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'''XYLOSE ISOMERASE FROM THERMOTOGA NEAPOLITANA'''<br />
 
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==About this Structure==
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==XYLOSE ISOMERASE FROM THERMOTOGA NEAPOLITANA==
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1A0E is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_neapolitana Thermotoga neapolitana] with <scene name='pdbligand=CO:'>CO</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Xylose_isomerase Xylose isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.5 5.3.1.5] Known structural/functional Sites: <scene name='pdbsite=CO1:Co+Binding+Site+1+Of+Molecule+A'>CO1</scene>, <scene name='pdbsite=CO2:Co+Binding+Site+2+Of+Molecule+A+(Hoh629+Was+Added+After+...'>CO2</scene>, <scene name='pdbsite=CO3:Co+Binding+Site+3+Of+Molecule+A+(Site+Co3+Is+On+A+Crysta+...'>CO3</scene>, <scene name='pdbsite=CO4:Co+Binding+Site+1+Of+Molecule+D'>CO4</scene>, <scene name='pdbsite=CO5:Co+Binding+Site+2+Of+Molecule+D+(Hoh629+Was+Added+After+...'>CO5</scene> and <scene name='pdbsite=CO6:Co+Binding+Site+3+Of+Molecule+D+(Site+Co3+Is+On+A+Crysta+...'>CO6</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A0E OCA].
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<StructureSection load='1a0e' size='340' side='right'caption='[[1a0e]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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[[Category: Single protein]]
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== Structural highlights ==
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[[Category: Thermotoga neapolitana]]
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<table><tr><td colspan='2'>[[1a0e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_neapolitana Thermotoga neapolitana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A0E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A0E FirstGlance]. <br>
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[[Category: Xylose isomerase]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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[[Category: Blow, D.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
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[[Category: Brick, P.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a0e OCA], [https://pdbe.org/1a0e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a0e RCSB], [https://www.ebi.ac.uk/pdbsum/1a0e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a0e ProSAT]</span></td></tr>
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[[Category: Chopra, R.]]
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</table>
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[[Category: Conti, E.]]
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== Function ==
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[[Category: Gallay, O.]]
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[https://www.uniprot.org/uniprot/XYLA_THENE XYLA_THENE]
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[[Category: CO]]
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== Evolutionary Conservation ==
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[[Category: alpha-beta barrel]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: glucose-fructose interconversion]]
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Check<jmol>
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[[Category: hydride transfer]]
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<jmolCheckbox>
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[[Category: ketolisomerase]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a0/1a0e_consurf.spt"</scriptWhenChecked>
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[[Category: metalloenzyme]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: thermophile]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: xylose metabolism]]
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a0e ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 09:28:35 2008''
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==See Also==
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*[[D-xylose isomerase 3D structures|D-xylose isomerase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Thermotoga neapolitana]]
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[[Category: Blow D]]
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[[Category: Brick P]]
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[[Category: Chopra R]]
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[[Category: Conti E]]
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[[Category: Gallay O]]

Current revision

XYLOSE ISOMERASE FROM THERMOTOGA NEAPOLITANA

PDB ID 1a0e

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