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3pbc

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[[Image:3pbc.jpg|left|200px]]
 
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==Peptidase module of the peptidoglycan hydrolase RipA (Rv1477) from Mycobacterium tuberculosis at 1.38 resolution==
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The line below this paragraph, containing "STRUCTURE_3pbc", creates the "Structure Box" on the page.
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<StructureSection load='3pbc' size='340' side='right'caption='[[3pbc]], [[Resolution|resolution]] 1.38&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3pbc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PBC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PBC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.38&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pbc OCA], [https://pdbe.org/3pbc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pbc RCSB], [https://www.ebi.ac.uk/pdbsum/3pbc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pbc ProSAT]</span></td></tr>
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{{STRUCTURE_3pbc| PDB=3pbc | SCENE= }}
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</table>
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== Function ==
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===Peptidase module of the peptidoglycan hydrolase RipA (Rv1477) from Mycobacterium tuberculosis at 1.38 resolution===
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[https://www.uniprot.org/uniprot/RIPA_MYCTU RIPA_MYCTU] Peptidoglycan endopeptidase that cleaves the bond between D-glutamate and meso-diaminopimelate. Binds and degrades high-molecular weight peptidoglycan from a number of Actinobacteria; activity is increased in the presence of RpfB and inhibited by PBP1A (ponA1). Required for normal separation of daughter cells after cell division and for cell wall integrity. Required for host cell invasion and intracellular survival in host macrophages.<ref>PMID:16495549</ref> <ref>PMID:17919286</ref> <ref>PMID:18463693</ref> <ref>PMID:20826344</ref> <ref>PMID:21864539</ref>
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[3pbc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PBC OCA].
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Both, D.]]
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[[Category: Both D]]
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[[Category: Schneider, G.]]
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[[Category: Schneider G]]
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[[Category: Schnell, R.]]
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[[Category: Schnell R]]
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[[Category: Cell wall]]
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[[Category: Extracellular]]
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[[Category: Hydrolase]]
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[[Category: Nlpc -like module]]
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[[Category: Peptidoglycan hydrolase]]
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[[Category: Petidoglycan]]
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Current revision

Peptidase module of the peptidoglycan hydrolase RipA (Rv1477) from Mycobacterium tuberculosis at 1.38 resolution

PDB ID 3pbc

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