3taj

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[[Image:3taj.jpg|left|200px]]
 
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==Crystal structure of C-lobe of bovine lactoferrin complexed with Nabumetone at 1.7A resolution==
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The line below this paragraph, containing "STRUCTURE_3taj", creates the "Structure Box" on the page.
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<StructureSection load='3taj' size='340' side='right'caption='[[3taj]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3taj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TAJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TAJ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NBO:NABUMETONE'>NBO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_3taj| PDB=3taj | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3taj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3taj OCA], [https://pdbe.org/3taj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3taj RCSB], [https://www.ebi.ac.uk/pdbsum/3taj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3taj ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRFL_BOVIN TRFL_BOVIN] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> Lactotransferrin has antimicrobial activity. The most effective inhibitory activity was seen against E.coli and P.aeruginosa.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> Lactoferricin B is an antimicrobial peptide. Inhibits the growth of Gram-negative and Gram-positive bacteria.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref>
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===Crystal structure of C-lobe of bovine lactoferrin complexed with Nabumetone at 1.7A resolution===
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==See Also==
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*[[Lactoferrin|Lactoferrin]]
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== References ==
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==About this Structure==
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<references/>
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[[3taj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TAJ OCA].
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__TOC__
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</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Gautam, L.]]
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[[Category: Large Structures]]
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[[Category: Kaur, P.]]
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[[Category: Gautam L]]
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[[Category: Sharma, S.]]
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[[Category: Kaur P]]
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[[Category: Singh, T P.]]
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[[Category: Sharma S]]
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[[Category: Sinha, M.]]
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[[Category: Singh TP]]
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[[Category: Yamini, S.]]
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[[Category: Sinha M]]
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[[Category: C-lobe]]
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[[Category: Yamini S]]
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[[Category: Hydrolase]]
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[[Category: Lactoferrin]]
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[[Category: Nabumetone]]
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[[Category: Nsaid]]
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Current revision

Crystal structure of C-lobe of bovine lactoferrin complexed with Nabumetone at 1.7A resolution

PDB ID 3taj

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