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3zyw
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3zyw is ON HOLD Authors: Vollmar, M., Johansson, C., Cocking, R., Krojer, T., Muniz, J.R.C., Kavanagh, K.L., Von Delft, F., Bountra, C., Arrowsmith,...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the first glutaredoxin domain of human glutaredoxin 3 (GLRX3)== | |
| - | + | <StructureSection load='3zyw' size='340' side='right'caption='[[3zyw]], [[Resolution|resolution]] 1.84Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3zyw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZYW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZYW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zyw OCA], [https://pdbe.org/3zyw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zyw RCSB], [https://www.ebi.ac.uk/pdbsum/3zyw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zyw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GLRX3_HUMAN GLRX3_HUMAN] Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Cocking R]] | ||
| + | [[Category: Edwards A]] | ||
| + | [[Category: Johansson C]] | ||
| + | [[Category: Kavanagh KL]] | ||
| + | [[Category: Krojer T]] | ||
| + | [[Category: Muniz JRC]] | ||
| + | [[Category: Oppermann U]] | ||
| + | [[Category: Vollmar M]] | ||
| + | [[Category: Weigelt J]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
Crystal structure of the first glutaredoxin domain of human glutaredoxin 3 (GLRX3)
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Cocking R | Edwards A | Johansson C | Kavanagh KL | Krojer T | Muniz JRC | Oppermann U | Vollmar M | Weigelt J | Von Delft F
