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2xpv

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[[Image:2xpv.jpg|left|200px]]
 
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==TetR(D) in complex with minocycline and magnesium.==
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The line below this paragraph, containing "STRUCTURE_2xpv", creates the "Structure Box" on the page.
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<StructureSection load='2xpv' size='340' side='right'caption='[[2xpv]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2xpv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XPV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XPV FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.49&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MIY:(4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE'>MIY</scene></td></tr>
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{{STRUCTURE_2xpv| PDB=2xpv | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xpv OCA], [https://pdbe.org/2xpv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xpv RCSB], [https://www.ebi.ac.uk/pdbsum/2xpv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xpv ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TETR4_ECOLX TETR4_ECOLX] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.
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===TETR(D) IN COMPLEX WITH MINOCYCLINE AND MAGNESIUM.===
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==See Also==
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*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 8153629 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8153629}}
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==About this Structure==
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[[2xpv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XPV OCA].
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==Reference==
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<ref group="xtra">PMID:008153629</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Dalm, D.]]
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[[Category: Large Structures]]
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[[Category: Hinrichs, W.]]
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[[Category: Dalm D]]
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[[Category: Palm, G J.]]
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[[Category: Hinrichs W]]
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[[Category: Proft, J.]]
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[[Category: Palm GJ]]
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[[Category: Helix-turn-helix]]
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[[Category: Proft J]]
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[[Category: Metal coordination]]
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[[Category: Transcription]]
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[[Category: Transcription regulator]]
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Current revision

TetR(D) in complex with minocycline and magnesium.

PDB ID 2xpv

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