3r27

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[[Image:3r27.jpg|left|200px]]
 
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==Crystal structure of the first RRM domain of heterogeneous nuclear ribonucleoprotein L (HnRNP L)==
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The line below this paragraph, containing "STRUCTURE_3r27", creates the "Structure Box" on the page.
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<StructureSection load='3r27' size='340' side='right'caption='[[3r27]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3r27]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R27 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R27 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_3r27| PDB=3r27 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r27 OCA], [https://pdbe.org/3r27 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r27 RCSB], [https://www.ebi.ac.uk/pdbsum/3r27 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r27 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HNRPL_HUMAN HNRPL_HUMAN] Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter.<ref>PMID:11809897</ref>
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===Crystal structure of the first RRM domain of heterogeneous nuclear ribonucleoprotein L (HnRNP L)===
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==See Also==
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*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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[[3r27]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R27 OCA].
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Li, X.]]
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[[Category: Large Structures]]
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[[Category: Liu, Y.]]
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[[Category: Li X]]
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[[Category: Niu, L.]]
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[[Category: Liu Y]]
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[[Category: Teng, M.]]
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[[Category: Niu L]]
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[[Category: Zeng, F.]]
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[[Category: Teng M]]
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[[Category: Zhang, W.]]
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[[Category: Zeng F]]
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[[Category: Nucleus]]
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[[Category: Zhang W]]
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[[Category: Protein binding]]
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[[Category: Rbd fold]]
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Current revision

Crystal structure of the first RRM domain of heterogeneous nuclear ribonucleoprotein L (HnRNP L)

PDB ID 3r27

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OCA

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