2jvw

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[[Image:2jvw.png|left|200px]]
 
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==Solution NMR structure of uncharacterized protein Q5E7H1 from Vibrio fischeri. Northeast Structural Genomics target VfR117==
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The line below this paragraph, containing "STRUCTURE_2jvw", creates the "Structure Box" on the page.
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<StructureSection load='2jvw' size='340' side='right'caption='[[2jvw]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2jvw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aliivibrio_fischeri_ES114 Aliivibrio fischeri ES114]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JVW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JVW FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jvw OCA], [https://pdbe.org/2jvw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jvw RCSB], [https://www.ebi.ac.uk/pdbsum/2jvw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jvw ProSAT], [https://www.topsan.org/Proteins/NESGC/2jvw TOPSAN]</span></td></tr>
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{{STRUCTURE_2jvw| PDB=2jvw | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DNABP_ALIF1 DNABP_ALIF1] Binds double-stranded DNA (dsDNA).<ref>PMID:21905121</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jv/2jvw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jvw ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Protein domain family PF09905 (DUF2132) is a family of small domains of unknown function that are conserved in a wide range of bacteria. Here we describe the solution NMR structure of the 80-residue VF0530 protein from Vibrio fischeri, the first structural representative from this protein domain family. We demonstrate that the structure of VF0530 adopts a unique four-helix motif that shows some similarity to the C-terminal double-stranded DNA (dsDNA) binding domain of RecA, as well as other nucleic acid binding domains. Moreover, gel shift binding data indicate a potential dsDNA binding role for VF0530. Proteins 2011; (c) 2011 Wiley-Liss, Inc.
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===Solution NMR structure of uncharacterized protein Q5E7H1 from Vibrio fischeri. Northeast Structural Genomics target VfR117===
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Solution NMR structure of VF0530 from Vibrio fischeri reveals a nucleic acid-binding function.,Aramini JM, Rossi P, Fischer M, Xiao R, Acton TB, Montelione GT Proteins. 2011 Oct;79(10):2988-91. doi: 10.1002/prot.23121. Epub 2011 Aug, 26. PMID:21905121<ref>PMID:21905121</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_21905121}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 2jvw" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 21905121 is the PubMed ID number.
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== References ==
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-->
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<references/>
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{{ABSTRACT_PUBMED_21905121}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Aliivibrio fischeri ES114]]
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[[2jvw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aliivibrio_fischeri Aliivibrio fischeri]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JVW OCA].
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[[Category: Large Structures]]
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[[Category: Acton TB]]
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==Reference==
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[[Category: Aramini JM]]
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<ref group="xtra">PMID:021905121</ref><references group="xtra"/>
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[[Category: Baran MC]]
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[[Category: Aliivibrio fischeri]]
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[[Category: Liu J]]
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[[Category: Acton, T B.]]
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[[Category: Montelione GT]]
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[[Category: Aramini, J M.]]
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[[Category: Nwosu C]]
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[[Category: Baran, M C.]]
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[[Category: Owens LA]]
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[[Category: Liu, J.]]
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[[Category: Rossi P]]
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[[Category: Montelione, G T.]]
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[[Category: Rost B]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Swapna GVT]]
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[[Category: Nwosu, C.]]
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[[Category: Wang D]]
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[[Category: Owens, L A.]]
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[[Category: Xiao R]]
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[[Category: Rossi, P.]]
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[[Category: Rost, B.]]
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[[Category: Swapna, G V.T.]]
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[[Category: Wang, D.]]
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[[Category: Xiao, R.]]
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[[Category: Alpha helical protein]]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Solution nmr structure]]
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[[Category: Structural genomic]]
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[[Category: Unknown function]]
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Current revision

Solution NMR structure of uncharacterized protein Q5E7H1 from Vibrio fischeri. Northeast Structural Genomics target VfR117

PDB ID 2jvw

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