3tq7
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3tq7 is ON HOLD Authors: De Groot, C.O., Scharer, M.A., Capitani, G., Steinmetz, M.O. Description: EB1c/EB3c heterodimer in complex with the CAP-Gl...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==EB1c/EB3c heterodimer in complex with the CAP-Gly domain of P150glued== | |
| + | <StructureSection load='3tq7' size='340' side='right'caption='[[3tq7]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3tq7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TQ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TQ7 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tq7 OCA], [https://pdbe.org/3tq7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tq7 RCSB], [https://www.ebi.ac.uk/pdbsum/3tq7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tq7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MARE1_HUMAN MARE1_HUMAN] Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.<ref>PMID:12388762</ref> <ref>PMID:21646404</ref> <ref>PMID:16109370</ref> <ref>PMID:19632184</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Dynactin|Dynactin]] | |
| - | + | *[[Dynein 3D structures|Dynein 3D structures]] | |
| + | *[[End-binding protein|End-binding protein]] | ||
| + | *[[Microtubule-associated protein 3D structures|Microtubule-associated protein 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Capitani G]] | ||
| + | [[Category: De Groot CO]] | ||
| + | [[Category: Scharer MA]] | ||
| + | [[Category: Steinmetz MO]] | ||
Current revision
EB1c/EB3c heterodimer in complex with the CAP-Gly domain of P150glued
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