4a16
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Structure of mouse Acetylcholinesterase complex with Huprine derivative== | |
+ | <StructureSection load='4a16' size='340' side='right'caption='[[4a16]], [[Resolution|resolution]] 2.65Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[4a16]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A16 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A16 FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=H34:(1-{4-[(7S,11S)-12-AMINO-3-CHLORO-6,7,10,11-TETRAHYDRO-7,11-METHANOCYCLOOCTA[B]QUINOLIN-9-YL]BUTYL}-1H-1,2,3-TRIAZOL-4-YL)METHANOL'>H34</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a16 OCA], [https://pdbe.org/4a16 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a16 RCSB], [https://www.ebi.ac.uk/pdbsum/4a16 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a16 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/ACES_MOUSE ACES_MOUSE] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. | ||
- | + | ==See Also== | |
- | + | *[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]] | |
- | + | __TOC__ | |
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Mus musculus]] | ||
+ | [[Category: Carletti E]] | ||
+ | [[Category: Colletier JP]] | ||
+ | [[Category: Jean L]] | ||
+ | [[Category: Nachon F]] | ||
+ | [[Category: Renard PY]] | ||
+ | [[Category: Ronco C]] | ||
+ | [[Category: Weik M]] |
Current revision
Structure of mouse Acetylcholinesterase complex with Huprine derivative
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Categories: Large Structures | Mus musculus | Carletti E | Colletier JP | Jean L | Nachon F | Renard PY | Ronco C | Weik M