This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3ow6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:36, 21 February 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3ow6.jpg|left|200px]]
 
-
<!--
+
==Crystal Structure of HSP90 with N-Aryl-benzimidazolone I==
-
The line below this paragraph, containing "STRUCTURE_3ow6", creates the "Structure Box" on the page.
+
<StructureSection load='3ow6' size='340' side='right'caption='[[3ow6]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3ow6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OW6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OW6 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MEX:1-(2,4-DIHYDROXYPHENYL)-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE'>MEX</scene></td></tr>
-
{{STRUCTURE_3ow6| PDB=3ow6 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ow6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ow6 OCA], [https://pdbe.org/3ow6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ow6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ow6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ow6 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>
-
===Crystal Structure of HSP90 with N-Aryl-benzimidazolone I===
+
==See Also==
-
 
+
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_21106457}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 21106457 is the PubMed ID number.
+
</StructureSection>
-
-->
+
-
{{ABSTRACT_PUBMED_21106457}}
+
-
 
+
-
==About this Structure==
+
-
[[3ow6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OW6 OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:021106457</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Park, C H.]]
+
[[Category: Large Structures]]
-
[[Category: Chaperone]]
+
[[Category: Park CH]]
-
[[Category: Hsp90]]
+

Current revision

Crystal Structure of HSP90 with N-Aryl-benzimidazolone I

PDB ID 3ow6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools