3ovu

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[[Image:3ovu.jpg|left|200px]]
 
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==Crystal Structure of Human Alpha-Haemoglobin Complexed with AHSP and the First NEAT Domain of IsdH from Staphylococcus aureus==
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The line below this paragraph, containing "STRUCTURE_3ovu", creates the "Structure Box" on the page.
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<StructureSection load='3ovu' size='340' side='right'caption='[[3ovu]], [[Resolution|resolution]] 2.83&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ovu]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MSSA476 Staphylococcus aureus subsp. aureus MSSA476]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OVU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OVU FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.83&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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{{STRUCTURE_3ovu| PDB=3ovu | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ovu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ovu OCA], [https://pdbe.org/3ovu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ovu RCSB], [https://www.ebi.ac.uk/pdbsum/3ovu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ovu ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AHSP_HUMAN AHSP_HUMAN] Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.<ref>PMID:12066189</ref>
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===Crystal Structure of Human Alpha-Haemoglobin Complexed with AHSP and the First NEAT Domain of IsdH from Staphylococcus aureus===
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==See Also==
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*[[Haptoglobin receptor|Haptoglobin receptor]]
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*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
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==About this Structure==
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== References ==
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[[3ovu]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OVU OCA].
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Staphylococcus aureus]]
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[[Category: Large Structures]]
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[[Category: Caradoc-Davies, T T.]]
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[[Category: Staphylococcus aureus subsp. aureus MSSA476]]
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[[Category: Gell, D A.]]
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[[Category: Caradoc-Davies TT]]
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[[Category: Guss, J M.]]
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[[Category: Gell DA]]
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[[Category: Jacques, D A.]]
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[[Category: Guss JM]]
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[[Category: Kumar, K Krishna.]]
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[[Category: Jacques DA]]
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[[Category: Langley, D B.]]
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[[Category: Krishna Kumar K]]
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[[Category: Mackay, J P.]]
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[[Category: Langley DB]]
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[[Category: Ahsp]]
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[[Category: Mackay JP]]
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[[Category: Haemoglobin]]
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[[Category: Host-pathogen interaction]]
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[[Category: Isdh]]
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[[Category: Neat domain]]
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[[Category: Oxygen transport-protein binding complex]]
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[[Category: Protein-protein complex]]
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Current revision

Crystal Structure of Human Alpha-Haemoglobin Complexed with AHSP and the First NEAT Domain of IsdH from Staphylococcus aureus

PDB ID 3ovu

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