3sqf
From Proteopedia
(Difference between revisions)
(5 intermediate revisions not shown.) | |||
Line 1: | Line 1: | ||
- | [[Image:3sqf.jpg|left|200px]] | ||
- | + | ==Crystal structure of monomeric M-PMV retroviral protease== | |
- | + | <StructureSection load='3sqf' size='340' side='right'caption='[[3sqf]], [[Resolution|resolution]] 1.63Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[3sqf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mason-Pfizer_monkey_virus Mason-Pfizer monkey virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SQF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SQF FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6324Å</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sqf OCA], [https://pdbe.org/3sqf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sqf RCSB], [https://www.ebi.ac.uk/pdbsum/3sqf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sqf ProSAT]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/PRO_MPMV PRO_MPMV] Matrix protein. Nucleocapsid protein p14: Nucleocapsid protein. Capsid protein. The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell.[PROSITE-ProRule:PRU00275]<ref>PMID:9636364</ref> The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell.[PROSITE-ProRule:PRU00275]<ref>PMID:9636364</ref> Enhances the activity of the reverse transcriptase. May be part of the mature RT.<ref>PMID:22171253</ref> | |
- | + | == References == | |
- | + | <references/> | |
- | < | + | __TOC__ |
- | + | </StructureSection> | |
- | + | [[Category: Large Structures]] | |
- | + | [[Category: Mason-Pfizer monkey virus]] | |
- | + | [[Category: Baker D]] | |
- | + | [[Category: Cooper S]] | |
- | == | + | [[Category: DiMaio F]] |
- | [[3sqf]] is a 2 chain structure with sequence from [ | + | [[Category: Gilski M]] |
- | + | [[Category: Group Foldit Contenders]] | |
- | == | + | [[Category: Jaskolski M]] |
- | < | + | [[Category: Kazmierczyk M]] |
- | [[Category: Mason- | + | [[Category: Khatib F]] |
- | [[Category: Baker | + | [[Category: Krzywda S]] |
- | [[Category: Cooper | + | [[Category: Pichova I]] |
- | [[Category: DiMaio | + | [[Category: Popovic Z]] |
- | [[Category: Gilski | + | [[Category: Thompson J]] |
- | [[Category: Group | + | [[Category: Zabranska H]] |
- | [[Category: Jaskolski | + | |
- | [[Category: Kazmierczyk | + | |
- | [[Category: Khatib | + | |
- | [[Category: Krzywda | + | |
- | [[Category: Pichova | + | |
- | [[Category: Popovic | + | |
- | [[Category: Thompson | + | |
- | [[Category: Zabranska | + | |
- | + | ||
- | + | ||
- | + | ||
- | + | ||
- | + | ||
- | + | ||
- | + |
Current revision
Crystal structure of monomeric M-PMV retroviral protease
|