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3tqu
From Proteopedia
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| - | [[Image:3tqu.jpg|left|200px]] | ||
| - | + | ==Structure of a HAM1 protein from Coxiella burnetii== | |
| - | + | <StructureSection load='3tqu' size='340' side='right'caption='[[3tqu]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3tqu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Coxiella_burnetii_RSA_493 Coxiella burnetii RSA 493]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TQU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TQU FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tqu OCA], [https://pdbe.org/3tqu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tqu RCSB], [https://www.ebi.ac.uk/pdbsum/3tqu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tqu ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/IXTPA_COXBU IXTPA_COXBU] Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.[HAMAP-Rule:MF_01405] | |
| - | + | __TOC__ | |
| - | == | + | </StructureSection> |
| - | [[3tqu]] is a 4 chain structure with sequence from [ | + | [[Category: Coxiella burnetii RSA 493]] |
| - | [[Category: Coxiella burnetii]] | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Burshteyn F]] |
| - | [[Category: Burshteyn | + | [[Category: Cassidy M]] |
| - | [[Category: Cassidy | + | [[Category: Cheung J]] |
| - | [[Category: Cheung | + | [[Category: Franklin MC]] |
| - | [[Category: Franklin | + | [[Category: Gary E]] |
| - | [[Category: Gary | + | [[Category: Love J]] |
| - | [[Category: Love | + | [[Category: Rudolph M]] |
| - | [[Category: Rudolph | + | |
| - | + | ||
| - | + | ||
Current revision
Structure of a HAM1 protein from Coxiella burnetii
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