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1eqd

From Proteopedia

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[[Image:1eqd.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF NITROPHORIN 4 COMPLEXED WITH CN==
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The line below this paragraph, containing "STRUCTURE_1eqd", creates the "Structure Box" on the page.
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<StructureSection load='1eqd' size='340' side='right'caption='[[1eqd]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1eqd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EQD FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=HEV:5,8-DIMETHYL-1,2,3,4-TETRAVINYLPORPHINE-6,7-DIPROPIONIC+ACID+FERROUS+COMPLEX'>HEV</scene></td></tr>
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{{STRUCTURE_1eqd| PDB=1eqd | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eqd OCA], [https://pdbe.org/1eqd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eqd RCSB], [https://www.ebi.ac.uk/pdbsum/1eqd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eqd ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eq/1eqd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eqd ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF NITROPHORIN 4 COMPLEXED WITH CN===
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==See Also==
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*[[Nitrophorin|Nitrophorin]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10876239}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 10876239 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10876239}}
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==About this Structure==
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[[1eqd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQD OCA].
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==Reference==
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<ref group="xtra">PMID:010876239</ref><references group="xtra"/>
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[[Category: Rhodnius prolixus]]
[[Category: Rhodnius prolixus]]
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[[Category: Andersen, J F.]]
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[[Category: Andersen JF]]
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[[Category: Montfort, W R.]]
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[[Category: Montfort WR]]
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[[Category: Roberts, S A.]]
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[[Category: Roberts SA]]
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[[Category: Weichsel, A.]]
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[[Category: Weichsel A]]
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[[Category: Beta barrel]]
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[[Category: Cyanide]]
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[[Category: Ferric heme]]
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[[Category: Lipocalin fold]]
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[[Category: Signaling protein]]
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Current revision

CRYSTAL STRUCTURE OF NITROPHORIN 4 COMPLEXED WITH CN

PDB ID 1eqd

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