3the

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[[Image:3the.png|left|200px]]
 
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==Crystal structure of Co2+2-HAI (pH 8.5)==
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The line below this paragraph, containing "STRUCTURE_3the", creates the "Structure Box" on the page.
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<StructureSection load='3the' size='340' side='right'caption='[[3the]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3the]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3THE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3THE FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.97&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCN:BICINE'>BCN</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
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{{STRUCTURE_3the| PDB=3the | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3the FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3the OCA], [https://pdbe.org/3the PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3the RCSB], [https://www.ebi.ac.uk/pdbsum/3the PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3the ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/ARGI1_HUMAN ARGI1_HUMAN] Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:[https://omim.org/entry/207800 207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia.<ref>PMID:1463019</ref> <ref>PMID:7649538</ref>
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== Function ==
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[https://www.uniprot.org/uniprot/ARGI1_HUMAN ARGI1_HUMAN]
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===Crystal structure of Co2+2-HAI (pH 8.5)===
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==See Also==
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*[[Arginase 3D structures|Arginase 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 21870783 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_21870783}}
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==About this Structure==
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[[3the]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3THE OCA].
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==Reference==
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<ref group="xtra">PMID:021870783</ref><references group="xtra"/>
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[[Category: Arginase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Antonio, E L.D.]]
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[[Category: Large Structures]]
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[[Category: Christianson, D W.]]
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[[Category: Christianson DW]]
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[[Category: Arginase fold]]
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[[Category: D'Antonio EL]]
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[[Category: Hydrolase]]
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Current revision

Crystal structure of Co2+2-HAI (pH 8.5)

PDB ID 3the

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OCA

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